GNE-049 at mesylate H2O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20

Name: GNE-049 at mesylate H2O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20
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H2O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20

Abrine is an alkaloid chemical marker and surrogate analyte of abrin

5(5):723-36

19(2):1288-1297

including HIV-1

GNE-049 at mesylate H2O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20GNE 049 is a highly potent and selective CBP inhibitor with an IC50 of 1. 1 nM in TR FRET assay. GNE 049 also inhibits BRET and BRD4(1) with IC50s of 12 nM and 4200 nM, respectively. Product information CAS Number: 1936421 41 8 Molecular Weight: 510. 58 Formula: C27H32F2N6O2 Chemical Name: 1 {3 [7 (difluoromethyl) 6 (1 methyl 1H pyrazol 4 yl) 1,2,3,4 tetrahydroquinolin 1 yl] 1 (oxan 4 yl) 1H,4H,5H,6H,7H pyrazolo[4,3 c]pyridin 5 yl}ethan 1 one Smiles:

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